Epidemiology of Mongolism

Fluorescent antibody techniques, immunochemical methods and progress in areas like gnotobiology and allergy have greatly expanded our knowledge in the serology of bacteria, and serological tools are now often used for classification and identification of bacteria. Thirteen specialists have contributed to this most impressive volume that presents the latest information in the field. A discussion of individual chapters cannot be possible; suffice it to say that thoroughness in compilation of factual knowledge and literature has been achieved. This makes it an indispensable part of a serological or bacteriological library. Particularly intriguing are those parts that present outlooks for further development in serology with regard to taxonomy and diagnosis (e.g., the analysis of Enterobacteriaceae antigens). Certain results still have to be presented in an "isolated" fashion, i.e. without integrating principles. This is inevitable, just as is the fact that the serological approach to bacterial taxonomy occasionally leads to conclusions different from those arrived at through biochemical and/or morphological research. It is also to be hoped that a uniform nomenclature for the antigens will be established. The authors have done an extremely valuable service to serology, bacteriology, and clinical science. ALEXANDER VON GRAEVENITZ